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Fibromyalgia is a disorder that causes widespread chronic pain and tenderness. According to the American College of Rheumatology, fibro (as many patients call it) is more common in women than in men and also common among people with arthritis or chronic pain, such as rheumatoid arthritis, ankylosing spondylitis, or lupus. Fibromyalgia can occur at any age but most often first strikes in middle age.