A Spanish study found that lupus patients given prednisone in medium dosages of 7.5 to 30 mg/day during their first month of treatment had an eight-fold higher likelihood of continuing on dosages above 7.5 mg/day throughout the first year compared with patients not on prednisone. The odds of staying on dosages above 7.5 mg/day were even greater for those starting treatment on high dosages above 30 mg/day. The researchers wrote that while glucocorticoids are one of the main therapies for lupus, “despite their proven efficacy, oral glucocorticoids are important predictors of irreversible damage in lupus.”


Click here for more.