The European League Against Rheumatism (EULAR) has updated its recommendations for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, focusing on remission induction, maintenance, and long-term concerns. With almost 1,700 papers on systemic vasculitis having been published during the past 5 years, these recommendations, an update of the EULAR 2009 recommendations, are based on increased knowledge of this challenging disease.