Chikungunya virus should be included in the differential for patients who present with new-onset symmetrical arthritis, especially if the individual has recently traveled to the Caribbean, researchers advised. Among a group of 10 individuals who visited Haiti in June 2014, eight developed persistent arthritis that mimicked seronegative rheumatoid arthritis, and the use of immunosuppressive therapies could have been “deleterious because viral RNA and antigens can be found in target tissues in the chronic phase,” wrote Wayne M. Yokoyama, MD, and colleagues from Washington University in St. Louis.

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